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Scientific contribution

CIC 1402
Laboratoire MOVE
Working group Physical Activity and Diabetes
Financial support

CHU de Poitiers
Pierre Fabre

What is actiDiaNe ?

actiDiaNe is a clinical study conducted in various hospitals and sports centers throughout France (and beyond) The objective of this study is to determine the effectiveness of a high-intensity physical activity program on kidney function in patients with type 2 diabetes and a rapid decline in renal function.

Read more about the study and diabetes

actiDiaNe through the media

We are proud to be able to broadcast the television recording produced by AllôDocteur. (Source: France5 on 20/10/2017) This is a great opportunity to communicate our goals but also to remind that this is a clinical study conducted in various hospitals and sports centers throughout France (and beyond).

Diabetes and sport

What we already know ...

Previously several studies have shown the beneficial effect of sport in people with type 2 diabetes. The image below shows the effect of physical activity on reducing the incidence of type 2 diabetes compared to Metformin, an anti-diabetic drug.

GLUT 4 allows the entry of glucose into the cells where it will be used to prevent accumulation in the vessels. An increase in the level of a glucose transporter named GLUT 4 has been observed during physical exercise in humans (with or without type 2 diabetes). This large increase in GLUT 4 induces a decrease in glucose in the blood and therefore an improvement in diabetes.

How does it work ?

The physical activity allows a better oxygenation of the tissues, preserves the function of the endothelium of the vessels (the inner wall), decreases oxidative stress and promotes the development of new blood capillaries. In addition, physical activity reduces the viscosity of the blood and has a beneficial effect on the tone of the vessels.

Diabetes, obesity and sport ...

There have also been studies showing the effect of physical activity on body weight in obese or overweight people, demonstrating the positive impact in the treatment of diabetes.

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